Peptide Database

Peptide NameNisin S

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC144H241N41O45S7

DescriptionStandard

        ITSYSLCTPGCKTGALMGCTMKTASCGCHVHISK
    

Molecular Weight3491.16 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0847

GRAVY Index0.34

Hydrophobic Moment 0.30

Boman Index0.18

Instability Index55.99

Aliphatic Index 60.29

Aromaticity 0.0294

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1352.55

LogP -18.40

H-bond Donors 54.0

H-bond Acceptors 57.0

Rotatable Bonds 113.0

Heavy Atoms 237.0

Ring Count 4.0

Amide Bonds 33.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0275602 VERIFIED: YES

Provenance & Taxonomy

OrganismLigilactobacillus salivarius [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

Targetindicator Gram-positive strains Enterococcus faecalis 12Ep11 (+++), L. seeligeri CECT 917 (+++), Listeria monocytogenes CECT 4032 (++), L. innocua CECT 910 (++), Staphylococcus aureus ZTA11/00117ST