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MYP_011617
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C111H192N28O21
Standard
Sequence
KWKLFKKIGIGAVLKVLKKG
Physicochemical Analysis
2254.89 Da
10.78
6.75
6.54
0.3377
0.20
0.59
0.08
-31.98
131.50
0.1000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
814.15
-1.06
29.0
28.0
83.0
160.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187412 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin A-Magainin 2 hybrid peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial
NCI-H128 (lung cancer)
3.5 μM
IC50
PaperStructure-antitumor and hemolytic activity relationships of synthetic peptides derived from cecropin A-magainin 2 and cecropin A-melittin hybrid peptides | https://pubmed.ncbi.nlm.nih.gov/9352466/ PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0219139 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin A-Magainin 2 hybrid peptides
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial
NCI-H69 (lung cancer)
3.4 μM
IC50
PaperStructure-antitumor and hemolytic activity relationships of synthetic peptides derived from cecropin A-magainin 2 and cecropin A-melittin hybrid peptides | https://pubmed.ncbi.nlm.nih.gov/9352466/ PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0258529 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0263637 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Cecropin
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial
NCI-H69
3.4 μM
IC50
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0277635 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
CA-MA / CA-ME / cecropin-magainin hybrid
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
NCI-H146
4.5 μM
IC50 / MTT-MTS assay
PaperPMID 9352466; CA-MA/CA-ME analog P1 report PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
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