Peptide Database

Peptide NameCHIPS-(28-149)

Function Ontology

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length122 amino acids

Chemical FormulaC644H1001N161O193S3

DescriptionStandard

        AFTFEPFPTNEEIESNKKMLEKEKAYKESFKNSGLPTTLGKLDERLRNYLKKGTKNSAQFEKMVILTENKGYYTVYLNTPLAEDRKNVELLGKMYKTYFFKKGESKSSYVINGPGKTNEYAY
    

Molecular Weight14183.00 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)5.81

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.0476

GRAVY Index-0.92

Hydrophobic Moment 0.68

Boman Index-0.15

Instability Index38.55

Aliphatic Index 58.36

Aromaticity 0.1393

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 14900.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5837.55

LogP -53.48

H-bond Donors 200.0

H-bond Acceptors 202.0

Rotatable Bonds 487.0

Heavy Atoms 1001.0

Ring Count 22.0

Amide Bonds 132.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0195745 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Chemotactic Immunomodulatory Signaling peptide

TargetC5a2 receptor (Human)

Activity274 nM

MethodIC50