Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC477H773N123O136S8

DescriptionStandard

        MKLFLVLIILQFEIPTDTARPRKCFSNITGYCRKKCQMGEIYEIACPNGKLCCVNEDKNKKYKKAPESPHSLPQPDEKIDYVILPTTTLLTVQ
    

Molecular Weight10663.50 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)3.53

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0380

GRAVY Index-0.32

Hydrophobic Moment 0.50

Boman Index-0.03

Instability Index45.37

Aliphatic Index 86.99

Aromaticity 0.0753

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4171.74

LogP -34.51

H-bond Donors 145.0

H-bond Acceptors 149.0

Rotatable Bonds 355.0

Heavy Atoms 744.0

Ring Count 16.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387431 VERIFIED: NO

Provenance & Taxonomy

OrganismAiluropoda melanoleuca [Animal]

FamilyDefensin

Tax ID9646

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence