Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC163H251N49O48S7

DescriptionStandard

        DHYMCVRNGGFCLYSSCPVNTKITGTCYHGRAKCC
    

Molecular Weight3889.49 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0820

GRAVY Index-0.18

Hydrophobic Moment 0.34

Boman Index-0.01

Instability Index57.61

Aliphatic Index 41.71

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1562.45

LogP -19.17

H-bond Donors 62.0

H-bond Acceptors 60.0

Rotatable Bonds 122.0

Heavy Atoms 267.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0308954 VERIFIED: YES

Provenance & Taxonomy

OrganismIctidomys tridecemlineatus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)