Peptide Database

Peptide NameLPcin-YK3 (bovine cathelicidin, cattle, ruminant, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC101H161N23O24S2

DescriptionStandard

        MNKVKEWIKYLKSLFSM
    

Molecular Weight2145.63 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.27

Charge Density (pH 7.0) 0.1470

GRAVY Index-0.21

Hydrophobic Moment 0.69

Boman Index0.01

Instability Index-2.18

Aliphatic Index 85.88

Aromaticity 0.1765

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 789.87

LogP -2.39

H-bond Donors 28.0

H-bond Acceptors 29.0

Rotatable Bonds 75.0

Heavy Atoms 150.0

Ring Count 4.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016934 VERIFIED: YES

Provenance & Taxonomy

OrganismBovine Lactophoricin [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEscherichia coli KCCM 41290

Activity1.25 μg/mL

MethodMIC

RECORD: Rec_0027436 VERIFIED: YES

Provenance & Taxonomy

OrganismBovine Lactophoricin [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

RECORD: Rec_0050329 VERIFIED: YES

Provenance & Taxonomy

OrganismBovine Lactophoricin [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStreptococcus mutans KCCM 40105

Activity1.25 μg/mL

MethodMIC

RECORD: Rec_0133500 VERIFIED: YES

Provenance & Taxonomy

OrganismBovine Lactophoricin [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetPorphyromonas gingvalis KCTC 5352

Activity0.62 μg/mL

MethodMIC

RECORD: Rec_0153513 VERIFIED: YES

Provenance & Taxonomy

OrganismBovine Lactophoricin [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

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