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MYP_011532
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Basic Information
Myeloid cathelicidin 3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C204H350N70O54S
Standard
Sequence
KRFHSVGSLIQRHQQMIRDKSEATRHGIRIITRPKLLLAS
Physicochemical Analysis
4679.46 Da
12.00
7.02
6.66
0.1756
-0.56
0.83
-0.24
30.89
100.00
0.0250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2050.18
-21.09
75.0
65.0
164.0
329.0
5.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018019 VERIFIED: NO
Provenance & Taxonomy
Equus caballus [Animal]
Cathelicidin
9796
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
RECORD: Rec_0079301 VERIFIED: NO
Provenance & Taxonomy
Equus caballus [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperMyeloid cathelicidin 3 Evidence URLhttps://www.uniprot.org/uniprotkb/O62842/entry
RECORD: Rec_0119330 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C.parapsilosis
>114 μg/mL
MIC
PaperNovel cathelicidins in horse leukocytes.
RECORD: Rec_0169965 VERIFIED: YES
Provenance & Taxonomy
Equus asinus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
but not Candida albicans
>114 μg/mL
MIC
PaperNovel cathelicidins in horse leukocytes.
RECORD: Rec_0173617 VERIFIED: YES
Provenance & Taxonomy
Equus caballus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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