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MYP_011531
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Basic Information
α4-short (Derived from α4)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C126H214N32O29
Standard
Sequence
LKKWWKTSKGLLGGLLGKVTSVIK
Physicochemical Analysis
2641.24 Da
10.70
5.75
5.54
0.2398
0.09
0.56
0.12
-6.50
121.67
0.0833
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1001.24
-5.37
37.0
35.0
93.0
187.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0370274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thionin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa strain 152-19
2 μM
MIC
PMID30967458 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30967458/
RECORD: Rec_0374728 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thionin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae strain A2
4 μM
MIC
PMID30967458 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30967458/
RECORD: Rec_0378307 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 0038-13
2 μM
MIC
PMID30967458 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30967458/
RECORD: Rec_0378485 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
PaperPatent US 2020/0079827 A1 Evidence URLhttps://patents.google.com/patent/US20200079827A1/en PatentUS 2020/0079827 A1
RECORD: Rec_0383011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thionin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa strain 16-21
2 μM
MIC
PMID30967458 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30967458/
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