Peptide Database

Peptide NameEndothelin

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC114H165N25O31S4

DescriptionStandard

        CSCATFLDKECVYFCHLDIIW
    

Molecular Weight2509.94 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.1043

GRAVY Index0.80

Hydrophobic Moment 0.30

Boman Index0.31

Instability Index56.15

Aliphatic Index 92.86

Aromaticity 0.1905

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 888.40

LogP -3.89

H-bond Donors 35.0

H-bond Acceptors 34.0

Rotatable Bonds 77.0

Heavy Atoms 174.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378416 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus mykiss,Salmo gairdneri [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Neuropeptide