Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC730H1148N218O218S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKANMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPQQMSALNGLLHELRGTYPKAVIMAHHDVAPKACPSFDLQRWVKTGELVTSDRG
    

Molecular Weight16690.71 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.10

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0139

GRAVY Index-0.43

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index40.35

Aliphatic Index 72.91

Aromaticity 0.0728

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7028.44

LogP -76.37

H-bond Donors 246.0

H-bond Acceptors 234.0

Rotatable Bonds 555.0

Heavy Atoms 1173.0

Ring Count 26.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425958 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage K11 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic