Peptide Database

Peptide NameGrowth hormone-releasing peptide-related peptide 3, fGRP-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC100H147N27O27

DescriptionStandard

        AQYTNHFVHSLDTLPLRF
    

Molecular Weight2159.40 Da

Isoelectric Point (pI)6.96

Net Charge (pH 7.0)-0.03

Net Charge (pH 7.4) -0.32

Charge Density (pH 7.0) -0.0016

GRAVY Index-0.19

Hydrophobic Moment 0.44

Boman Index0.08

Instability Index-0.52

Aliphatic Index 86.67

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 872.89

LogP -7.04

H-bond Donors 30.0

H-bond Acceptors 29.0

Rotatable Bonds 65.0

Heavy Atoms 154.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025583 VERIFIED: NO

Provenance & Taxonomy

OrganismRana catesbeiana [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0076293 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0307515 VERIFIED: NO

Provenance & Taxonomy

OrganismAquarana catesbeiana [Animal]

FamilyfGRP-related peptide

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0416662 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates catesbeiana [Animal]

FamilyFMRFamide related peptide

Tax ID8400

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator