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MYP_011478
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Basic Information
SARSWW-I
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C111H160N24O26S
Standard
Sequence
MWKTPTLKYFGGFNFSQIL
Physicochemical Analysis
2278.67 Da
9.70
1.50
1.28
0.0788
0.04
0.25
0.26
23.86
61.58
0.2632
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
813.26
-3.66
28.0
29.0
71.0
162.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0174254 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
S2-derived peptide
694009
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
PaperInhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
RECORD: Rec_0244374 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV
50-60 % Inhibition
Inhibition
PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
RECORD: Rec_0251287 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
SARS-CoV
PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
RECORD: Rec_0299846 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-SARS-CoV Entry inhibition
SARS-CoV | Vero-E6 cells
30 μM
% inhibition
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. | Sainz B Jr, Mossel EC, Gallaher WR, Wimley WC, Peters CJ, Wilson RB, Garry RF. | Virus Res. 2006 Sep;120(1-2):146-55. | DOI:10.1016/j.virusres.2006.03.001 | PMID:16616792 PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
RECORD: Rec_0329969 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID16616792 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16616792/
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