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MYP_011477
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Basic Information
HBD3 [C11,18,23,33,40,41A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
45 amino acids
C216H377N75O59
Standard
Sequence
GIINTLQKYYARVRGGRAAVLSALPKEEQIGKASTRGRKAARRKK
Physicochemical Analysis
4968.77 Da
11.65
10.76
10.54
0.2391
-0.79
0.65
-0.32
46.87
80.44
0.0444
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2249.60
-25.48
83.0
70.0
176.0
350.0
3.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032299 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922[LC = 24.9 microg/ml
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0040983 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0072466 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
20.8 μg/mL
LC50
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0116376 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus NCTC 2599
19.6 μg/mL
LC50
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0138436 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2010/0048469 A1 Evidence URLhttps://patents.google.com/patent/US20100048469A1/en PatentUS 2010/0048469 A1
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