Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length390 amino acids

Chemical FormulaC1946H3115N495O546S15

DescriptionStandard

        MFLWCVLVLLNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALVLVPDTGVMLSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVMSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQICPLVADSIGEFYNIGQHKEPPFSPTPFSLPSQDTDMLYIGVSAFTINSAGFVYNRAGALHLYITDDMIPSGSPIRLNTKTFGAFIPQIEKMYPGLMMKLLVETVKDTLSPLFVLNLIQTIILLNRINMSLAKSYVGPFQVTSLDNIFTIVLKFAVIPKVNARLQEGYPLPAIGKMQLVNSQLKVLKDYLLIGTDVQFTG
    

Molecular Weight42662.51 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)9.82

Net Charge (pH 7.4) 9.28

Charge Density (pH 7.0) 0.0252

GRAVY Index0.29

Hydrophobic Moment 0.72

Boman Index0.19

Instability Index28.88

Aliphatic Index 109.67

Aromaticity 0.0872

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 35995.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370856 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria