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MYP_011339
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Basic Information
C18-c01r
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H1N1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Binding inhibition
Standard
15 amino acids
C80H118N24O18
Standard
Sequence
AVASVPRARGKYWWG
Physicochemical Analysis
1703.94 Da
11.00
2.79
2.60
0.1863
-0.36
0.27
0.02
-8.00
58.67
0.2000
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
683.79
-4.63
26.0
21.0
49.0
122.0
6.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0113533 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Alkylated(C18)
Amidation
Alkylated(C18)
Bio-Activity Profile
Antiviral Anti-H3N2 Binding inhibition
H3N2 (A/Aichi/2/68)
17 μM
IC50
Mammalian: 4.4 h; Yeast: >20 h; E. coli: >10 h
PaperInhibition of influenza virus infections by sialylgalactose-binding peptides selected from a phage library. | Matsubara T, Sumi M, Kubota H, Taki T, Okahata Y, Sato T. | J Med Chem. 2009 Jul 23;52(14):4247-56. | DOI:10.1021/jm801570y | PMID:19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0180626 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Alkylated(C18)
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
H1N1(A/PR/8/34):inhibition of virus infection in Madin-Darby canine kidney(MDCK) cells
44 μM
IC50
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0232247 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Alkylated(C18)
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
RECORD: Rec_0298352 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0333289 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Alkylated(C18)
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
H3N2(A/Aichi/2/68):inhibition of virus infection in Madin-Darby canine kidney(MDCK) cells
17 μM
IC50
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
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