Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC424H675N117O125S15

DescriptionStandard

        MKAFSIAVAVTLVLAFICVLESSAVPFTGVQEQEEAGSNDTPVAAHQEMSMESWMMPNLIRKKRQSHLSMCRYCCNCCKNKGCGYCCKF
    

Molecular Weight9892.58 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)1.60

Net Charge (pH 7.4) 1.12

Charge Density (pH 7.0) 0.0179

GRAVY Index0.08

Hydrophobic Moment 0.54

Boman Index0.07

Instability Index52.35

Aliphatic Index 66.85

Aromaticity 0.0787

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3881.53

LogP -40.49

H-bond Donors 142.0

H-bond Acceptors 144.0

Rotatable Bonds 329.0

Heavy Atoms 681.0

Ring Count 13.0

Amide Bonds 96.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0387617 VERIFIED: NO

Provenance & Taxonomy

OrganismKryptolebias marmoratus [Bacterium]

FamilyHepcidin

Tax ID37003

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal