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MYP_011308
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Basic Information
p2-p10
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition ▸ Release inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
10 amino acids
C53H82N16O14
Standard
Sequence
PYVGSGLYRR
Physicochemical Analysis
1167.32 Da
10.00
1.96
1.90
0.1956
-0.68
0.39
-0.15
40.88
68.00
0.2000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
495.72
-4.43
20.0
16.0
35.0
83.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019535 VERIFIED: YES
Provenance & Taxonomy
Avian myeloblastosis-associated virus [Virus]
Virus-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibitor Release inhibitor
Avian myeloblastosis virus (Release)
50 μM
Protease activity assay
PaperMechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins. | Cameron CE, Grinde B, Jentoft J, Leis J, Weber IT, Copeland TD, Wlodawer A. | J Biol Chem. 1992 | PMID:1331099 PMID1331099 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1331099/
RECORD: Rec_0050281 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/