Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

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Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC130H211N35O38S6

DescriptionStandard

        GIPCGESCVWIPCITSAIGCSCKSKVCYR
    

Molecular Weight3064.67 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0586

GRAVY Index0.58

Hydrophobic Moment 0.35

Boman Index0.20

Instability Index14.71

Aliphatic Index 77.24

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1148.95

LogP -12.62

H-bond Donors 47.0

H-bond Acceptors 46.0

Rotatable Bonds 95.0

Heavy Atoms 209.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035594 VERIFIED: YES

Provenance & Taxonomy

OrganismViola biflora [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)