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MYP_011282
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
31 amino acids
C134H217N35O42S6
Standard
Sequence
GSIPCGESCVFIPCISAVIGCSCSNKVCYKN
Physicochemical Analysis
3182.76 Da
7.77
0.70
0.40
0.0226
0.72
0.31
0.26
30.24
81.61
0.0645
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1215.64
-15.37
47.0
49.0
100.0
217.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133386 VERIFIED: YES
Provenance & Taxonomy
Viola philippica [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
Cancer cell lines: MM96L
2.51±0.03 μM
IC50
PaperPubMed PMID: 21723349 PMID21723349 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21723349/
RECORD: Rec_0163840 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 45.2%, T 35.5%, C 19.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0180066 VERIFIED: NO
Provenance & Taxonomy
Viola philippica [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
disulfide-stabilized; exact pairings not extracted
cystine-knot scaffold
Bio-Activity Profile
Anticancer Antimicrobial
PaperPlant Antimicrobial Oligopeptides with Anticancer Properties as a Source of Biologically Active Peptides—An In Silico Study PMID41009751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/41009751/
RECORD: Rec_0194666 VERIFIED: YES
Provenance & Taxonomy
Viola philippica [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
HeLa
5.24±0.4 μM
IC50
PaperPubMed PMID: 21723349 PMID21723349 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21723349/
RECORD: Rec_0215355 VERIFIED: YES
Provenance & Taxonomy
Viola philippica [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21723349 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21723349/
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