Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length478 amino acids

Chemical FormulaC2368H3719N609O671S15

DescriptionStandard

        MSKARNLLLASLLLCLHYSPLSGATGPGFVGRITDKGLDYARQEGVAALQQKLAQLTLPDFSGSFRVKVIGRVDYKLYSLNIRSFQLPSSAIAPVPGTGLKVSITNAFAEVTGDWLVKKRWFKDHGSFDLKVEGISISVGLKLGADASGRPTVGTADCAAHISDVKVHFSGRLSWLYNLFHKNIESSFRNTMEGKVCEEVSSSIGSKLQPFLQTLPVTARIDKVSGIDYSLVAPPVASQNSLDLDLKGEFFSLAHRSAPPFTPPALAFPVDHDRMLYFGISTYFFNTAGLVYYGAGEMNFFITDDMVPKEFKVRLNTTCFKPFVPQLEKLYPNMLMKLQVSPSSAPSLTITPDAISLSPAVDIRAFAILPNASLASLFVIGASTTMSAKVSVNSTKIFGSLKLGKLQLSLKHSDVGPFSVQLMEAIMNYLASSTLLPAMNARLAEGFPLPLPDHVELSSAFLQLRQDFLLFGADVRYG
    

Molecular Weight51936.51 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)7.27

Net Charge (pH 7.4) 6.44

Charge Density (pH 7.0) 0.0152

GRAVY Index0.16

Hydrophobic Moment 0.72

Boman Index0.15

Instability Index36.49

Aliphatic Index 96.92

Aromaticity 0.0983

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 36120.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0026287 VERIFIED: NO

Provenance & Taxonomy

OrganismPodarcis muralis (Wall lizard) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria