Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length531 amino acids

Chemical FormulaC2605H4136N716O725S21

DescriptionStandard

        MAGAAGPMAGAAVWGTAPTGHASRSQPVWLCFLLLLPTCVSATTTSPGIKVWLTQRTLEFGRRFGLELLQSMLQKEHELNLTGSYNTLLGTLTYAVPRIRIHELQMNESTLDFAEDVGLRLTVQRARVQLSADWAAQLGAVQDSGSVQLGMQDVAMAAVLGVSEDGGGHPTVWSAGCDTHGTDLHMEFHRGYSWLYNLLAPLLQRTLRQQLNKQLCLMLQRGIDRLDTALKHMKVSTQLDTIAAIDHSLLAPPAFTEEYGDIALKGEIFRVGTYQQRPPALPVALPVALPMALPVALPTALPTTPPMAHEPTLLLAVTEFVANSAAFTYFSAGALRRIISSDMVPRRFPLQLSTKSMGIFSPQLQELYPDQPMELHLWARQQPLLSCHPDALHGTLLGSAEAFVVLPNATRAPAFLLHIDANVTGKPTITRNRLGGTVRLTGLHITQVASNVGPVEVKRLETLLKFSLWLFGVPRANKWLQAGIPLPLPHGLSLLRPRLSLHQVGATTVPFPRGPPYPPCPPCPLSHPDSL
    

Molecular Weight57758.43 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)5.05

Net Charge (pH 7.4) 3.75

Charge Density (pH 7.0) 0.0095

GRAVY Index0.08

Hydrophobic Moment 0.76

Boman Index0.14

Instability Index44.85

Aliphatic Index 99.79

Aromaticity 0.0659

Extinction Coeff. Reduced 62910.00

Extinction Coeff. Oxidized 63285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0119466 VERIFIED: NO

Provenance & Taxonomy

OrganismJunco hyemalis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence