Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1327H2085N343O366S6

DescriptionStandard

        VTAKIDAKTGIDYSLVAPPRATAQSLDADLKGEFYSLGHRSTIPFSPLPLAFPADHDRMVYFGASSYFFNTAGIAYHKAGALVFEITEAMISKKAGFKLDTSVFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGHIVGSLDVGRIRLSLKDSAVGTFQVELLQSIMNILTSNVLLPRLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADIHFQPR
    

Molecular Weight28892.22 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)2.28

Net Charge (pH 7.4) 1.72

Charge Density (pH 7.0) 0.0086

GRAVY Index0.28

Hydrophobic Moment 0.61

Boman Index0.18

Instability Index38.80

Aliphatic Index 106.82

Aromaticity 0.0985

Extinction Coeff. Reduced 10430.00

Extinction Coeff. Oxidized 10430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374241 VERIFIED: NO

Provenance & Taxonomy

OrganismHylia prasina [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria