Peptide Database

Peptide NameBrevinin 2GHg

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC134H236N40O41S2

DescriptionStandard

        GLITDTLKGAAKTVAAELLRKAHCKLTNSC
    

Molecular Weight3127.68 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)2.83

Net Charge (pH 7.4) 2.54

Charge Density (pH 7.0) 0.0942

GRAVY Index0.12

Hydrophobic Moment 0.56

Boman Index0.02

Instability Index2.78

Aliphatic Index 104.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1320.72

LogP -14.91

H-bond Donors 49.0

H-bond Acceptors 47.0

Rotatable Bonds 108.0

Heavy Atoms 217.0

Ring Count 1.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0104745 VERIFIED: NO

Provenance & Taxonomy

OrganismHylarana guentheri [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0206207 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvirana guentheri [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)