Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC482H783N139O132S9

DescriptionStandard

        MKLLLLFLAIFLAVEPVMSEEECWSHGHCRLVCNDDEDHVLRCVNRKRCCVPSRYVTMKPITIDYVLDWTTPTVPTTVPTTVRKRKKNKKHGRG
    

Molecular Weight10925.81 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)5.80

Net Charge (pH 7.4) 5.27

Charge Density (pH 7.0) 0.0617

GRAVY Index-0.27

Hydrophobic Moment 0.66

Boman Index-0.09

Instability Index48.92

Aliphatic Index 85.85

Aromaticity 0.0638

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4352.03

LogP -37.38

H-bond Donors 160.0

H-bond Acceptors 151.0

Rotatable Bonds 358.0

Heavy Atoms 762.0

Ring Count 18.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213838 VERIFIED: NO

Provenance & Taxonomy

OrganismIctidomys tridecemlineatus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence