Peptide Database

Peptide NameMel(12-26, L8)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC77H141N25O19

DescriptionStandard

        GLPALISLIKRKRQQ
    

Molecular Weight1721.10 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2505

GRAVY Index-0.29

Hydrophobic Moment 0.57

Boman Index-0.19

Instability Index98.50

Aliphatic Index 136.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 744.18

LogP -6.12

H-bond Donors 26.0

H-bond Acceptors 23.0

Rotatable Bonds 61.0

Heavy Atoms 121.0

Ring Count 1.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402508 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

Targethuman erythrocytes

Activity9350 μg/mL

MethodHemolysis

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