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MYP_011070
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Basic Information
Mel(12-26, L8)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C77H141N25O19
Standard
Sequence
GLPALISLIKRKRQQ
Physicochemical Analysis
1721.10 Da
12.00
3.76
3.55
0.2505
-0.29
0.57
-0.19
98.50
136.67
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
744.18
-6.12
26.0
23.0
61.0
121.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0120957 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
161 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0168919 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
13.5 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0221516 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
9350 μg/mL
Paperhttps://pubmed.ncbi.nlm.nih.gov/14596922/ PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0321787 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
10 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0334775 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides (https://pubmed.ncbi.nlm.nih.gov/24174543/) PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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