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MYP_011064
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ HMG-CoA Reductase Inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Metabolic ▸ Lipid metabolism ▸ Lipid-lowering activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
8 amino acids
C33H58N8O10
Standard
Sequence
IAVPTGVA
Physicochemical Analysis
726.86 Da
5.53
-0.24
-0.44
-0.0300
1.73
0.09
0.67
22.21
146.25
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
278.46
-2.29
9.0
10.0
19.0
51.0
1.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0142022 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
106.0
IC50
PaperLammi C., Zanoni C., Arnoldi A., Vistoli G.. Peptides derived from soy and lupin protein as dipeptidyl-peptidase IV inhibitors: in vitro biochemical screening and in silico molecular modeling study. J. Agric. Food Chem., 2016, 64, 9601-9606.
RECORD: Rec_0152607 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
14.7
IC50
PaperDellafiora L., Pugliese R., Bollati C., Gelain F., Galaverna G., Arnoldi A., Lammi C.. "Bottom-Up" strategy for the identification of novel soybean peptides with angiotensin-converting enzyme inhibitory activity. J. Agric. Food Chem., 68, 2082-2090, 2020.
RECORD: Rec_0154103 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hypolipidemic HMG-CoA Reductase Inhibitory
HMG-CoA reductase
152.0
IC50
PaperPak V. V., Koo M., Lee N., Lee J. S., Kasimova T. D., Kwon D. Y.. Structure activity relationship of Ile-Ala-Val-Pro peptide and its derivatives by using semi-empirical AM1 method. Chem. Nat. Comp., 41, 454-460, 2005.
RECORD: Rec_0363723 VERIFIED: NO
Provenance & Taxonomy
Glycine max [Plant]
3847
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
Dipeptidyl peptidase IV