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MYP_010990
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Basic Information
m5 /GIn6
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
18 amino acids
C95H147N25O25S
Standard
Sequence
SKVNGASGRMEFFWTILK
Physicochemical Analysis
2071.40 Da
9.99
1.46
1.25
0.0812
-0.08
0.28
0.08
-10.71
65.00
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
828.83
-6.74
30.0
28.0
69.0
146.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033326 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Pseudovirus influenza A virus(HA(VN/04)/HIV)
PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
RECORD: Rec_0051790 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV Entry inhibition
Pseudovirus influenza A virus (HA (VN/04)/HIV)
30 μM
% inhibition
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperInfluenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | Influenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | ACS Infect Dis. 2016 Mar 11;2(3):187-93 | DOI:10.1021/acsinfecdis.5b00139 | PMID:27623031 PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
RECORD: Rec_0273916 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/