Peptide Database

Peptide NameExtended FMRFamide-10

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC54H84N18O19

DescriptionStandard

        PAASESGFRRDP
    

Molecular Weight1289.35 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0031

GRAVY Index-1.23

Hydrophobic Moment 0.27

Boman Index-0.33

Instability Index105.05

Aliphatic Index 16.67

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 599.50

LogP -8.57

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 39.0

Heavy Atoms 91.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0002178 VERIFIED: YES

Provenance & Taxonomy

OrganismMantophasma kudubergense [Animal]

FamilyExtended FMRFamide

Tax ID1037657

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: >20 hour; Yeast: >20 hour; E. coli: ?

RECORD: Rec_0294278 VERIFIED: NO

Provenance & Taxonomy

OrganismMantophasma kudubergense [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0299693 VERIFIED: YES

Provenance & Taxonomy

OrganismMantophasma kudubergense [Animal]

FamilyFMRFamide related peptide

Tax ID1037657

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0324618 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/