Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC568H897N161O159S14

DescriptionStandard

        MKLLVLFLAILLAIEEPVVSVECWMDGHCRLLCRDDEDSIIRCRNRKRHILLCMGNSGICRASCKKNEQPYFYCRNYQFCCLQSYMRISISGKEENTDWSYEKQWPRLP
    

Molecular Weight12974.09 Da

Isoelectric Point (pI)8.35

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.10

Charge Density (pH 7.0) 0.0238

GRAVY Index-0.29

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index72.55

Aliphatic Index 84.95

Aromaticity 0.1009

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5206.74

LogP -43.75

H-bond Donors 193.0

H-bond Acceptors 178.0

Rotatable Bonds 434.0

Heavy Atoms 902.0

Ring Count 20.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111776 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence