Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC537H869N153O146S8

DescriptionStandard

        MRLLLIIAILLFQKFTVTEQLKKCWGEYVRGYCRKICRTTEIREVLCENGRYCCLNIVEVEARRKITKPPRPKPLTYALTFPQDNYENERNYTRHKEKSM
    

Molecular Weight12061.10 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)8.54

Net Charge (pH 7.4) 8.15

Charge Density (pH 7.0) 0.0854

GRAVY Index-0.56

Hydrophobic Moment 0.79

Boman Index-0.19

Instability Index38.10

Aliphatic Index 83.80

Aromaticity 0.1000

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4918.29

LogP -39.47

H-bond Donors 180.0

H-bond Acceptors 164.0

Rotatable Bonds 407.0

Heavy Atoms 844.0

Ring Count 17.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040116 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence