MYP_010936
Albiglutide
Hormonal / Endocrine
▸
Hormone peptide
Metabolic
▸
Glucose metabolism
▸
Metabolic
▸
Glucose metabolism
▸
Antidiabetic
▸
Standard
645 amino acids
C3232H5066N864O979S41
Standard
HGEGTFTSDVSSYLEGQAAKEFIAWLVKGRHGEGTFTSDVSSYLEGQAAKEFIAWLVKGRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
73004.67 Da
5.66
-15.87
-17.76
-0.0246
-0.39
0.77
-0.06
36.65
76.12
0.0899
46300.00
48425.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0109197
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Insulin
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone replacement
4-7 days.
RECORD: Rec_0273446
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
GLP-1 receptor agonist fusion protein
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic
Hypoglycemic
GLP-1 receptor agonist
4-7 d.
RECORD: Rec_0431908
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GLP-1 receptor agonist
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Engineered tandem GLP-1 analog fused to human albumin
Bio-Activity Profile
Antidiabetic
Hypoglycemic
GLP-1 receptor agonist
patients with type 2 diabetes mellitus inadequately controlled with diet and exercise
-0.84 % HbA1c difference vs placebo
52-week randomized placebo-controlled clinical trial (30 mg once weekly)
RECORD: Rec_0431909
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GLP-1 receptor agonist
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Engineered tandem GLP-1 analog fused to human albumin
Bio-Activity Profile
Antidiabetic
Hypoglycemic
GLP-1 receptor agonist
patients with type 2 diabetes mellitus inadequately controlled with diet and exercise
-1.04 % HbA1c difference vs placebo
52-week randomized placebo-controlled clinical trial (50 mg once weekly)