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MYP_010930
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Basic Information
VEGF-P3(CYC)
Anticancer
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
16 amino acids
C83H143N23O21S3
Standard
Sequence
ITMQGIQGQKIRMIMF
Physicochemical Analysis
1895.36 Da
11.00
1.76
1.55
0.1099
0.38
0.23
0.18
-5.95
97.50
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
737.24
-4.81
25.0
26.0
68.0
130.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194563 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
VEGF mimetic
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Literature describes one intramolecular disulfide bond in the CYC construct
N-acetylated cyclic VEGF mimetic with one reported disulfide bridge.
Bio-Activity Profile
Anti-angiogenic Anticancer
Endothelial cells / tumor model
Migration assay
PaperVEGF peptide mimics and HER2/neu peptide vaccines with anti-angiogenic activity PMID23170253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23170253/
RECORD: Rec_0200374 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
VEGF mimetic
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Literature describes one intramolecular disulfide bond in the CYC construct
N-acetylated cyclic VEGF mimetic with one reported disulfide bridge.
Bio-Activity Profile
Anti-angiogenic Anticancer
Endothelial cells / tumor model
Network formation assay
PaperVEGF peptide mimics and HER2/neu peptide vaccines with anti-angiogenic activity PMID23170253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23170253/
RECORD: Rec_0206193 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
VEGF mimetic
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Literature describes one intramolecular disulfide bond in the CYC construct
N-acetylated cyclic VEGF mimetic with one reported disulfide bridge.
Bio-Activity Profile
Anti-angiogenic Anticancer
Endothelial cells / tumor model
Endothelial proliferation assay
PaperVEGF peptide mimics and HER2/neu peptide vaccines with anti-angiogenic activity PMID23170253 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23170253/
RECORD: Rec_0359986 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
RECORD: Rec_0402593 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer