Peptide Database

Peptide NameConotoxin-2/7

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC135H200N30O35S7

DescriptionStandard

        VCIADDMPCGFGLFGGPLCCSGWCLFVCL
    

Molecular Weight3027.67 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.32

Net Charge (pH 7.4) -2.62

Charge Density (pH 7.0) -0.0801

GRAVY Index1.42

Hydrophobic Moment 0.31

Boman Index0.55

Instability Index41.07

Aliphatic Index 90.69

Aromaticity 0.1379

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 971.16

LogP -5.57

H-bond Donors 38.0

H-bond Acceptors 40.0

Rotatable Bonds 89.0

Heavy Atoms 207.0

Ring Count 7.0

Amide Bonds 28.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0133780 VERIFIED: NO

Provenance & Taxonomy

OrganismConus imperialis [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-20; 9-24; 19-28

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0396087 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic