Peptide Database

Peptide NameAlpha-mammal toxin Ts3

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC330H481N81O101S8

DescriptionStandard

        KKDGYPVEYDNCAYICWNYDNAYCDKLCKDKKADSGYCYWVHILCYCYGLPDSEPTKTNGKCKS
    

Molecular Weight7455.35 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.64

Charge Density (pH 7.0) -0.0037

GRAVY Index-0.83

Hydrophobic Moment 0.34

Boman Index-0.11

Instability Index35.86

Aliphatic Index 44.22

Aromaticity 0.1719

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2955.97

LogP -26.57

H-bond Donors 109.0

H-bond Acceptors 110.0

Rotatable Bonds 237.0

Heavy Atoms 520.0

Ring Count 17.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162445 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide12-62; 16-38; 24-45; 28-47

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense