Peptide Database

Peptide NameProtegrin-4 (PG-4)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC726H1173N209O217S10

DescriptionStandard

        METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEVQGVRGGRLCYCRGWICFCVGRG
    

Molecular Weight16622.00 Da

Isoelectric Point (pI)7.45

Net Charge (pH 7.0)0.44

Net Charge (pH 7.4) 0.06

Charge Density (pH 7.0) 0.0029

GRAVY Index-0.25

Hydrophobic Moment 0.77

Boman Index-0.06

Instability Index30.10

Aliphatic Index 88.93

Aromaticity 0.0604

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6854.47

LogP -69.13

H-bond Donors 245.0

H-bond Acceptors 228.0

Rotatable Bonds 543.0

Heavy Atoms 1162.0

Ring Count 23.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190838 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic