Peptide Database

Peptide NameCHH-like protein

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC388H575N91O113S8

DescriptionStandard

        SFFTLECKGVFDAAIFARLDRICDDCFNLFREPQLYTLCRAECFTTPYFKGCMESLYLYDEKEQIDQMIDFV
    

Molecular Weight8578.78 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-6.58

Net Charge (pH 7.4) -6.90

Charge Density (pH 7.0) -0.0914

GRAVY Index0.02

Hydrophobic Moment 0.77

Boman Index0.06

Instability Index37.25

Aliphatic Index 73.19

Aromaticity 0.1806

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3297.06

LogP -22.81

H-bond Donors 119.0

H-bond Acceptors 115.0

Rotatable Bonds 280.0

Heavy Atoms 600.0

Ring Count 15.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024104 VERIFIED: YES

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyCHH-like protein

Tax ID7091

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0039931 VERIFIED: NO

Provenance & Taxonomy

OrganismBombyx mori [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID7091

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0121561 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/