Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length477 amino acids

Chemical FormulaC2356H3689N583O703S16

DescriptionStandard

        MLPSVVVLLMLLSSTCGEDPAIQLILTNKALSYGKAQAKDWIQQNLEHAHFPDISGNIDIGLGSVDYALTGITITKCDLPEPSVEFYPDITGFKTSIYGLSIALTGGWSTHYGLIHDSGSFDMAVLDVNVISAVELGKDPDGHLSVSSISCDAQVGDVDVQFHGGASWIFQPFVDFFKERISDEIQKRICPSVEEMIVKLESHLQAMNVSFDVNQVLSLDLHLTSLPVVASTSLNLGLKGEFYNIKTHSEPPFKLKSFTLPEQQGYMVSVGLSEFTLNSASYGYYSAGLLQADINDSMIPPYCPVHLNTTSVGRYIPQLPKLFPGLPMSLKVYAREVPVFSFQSDVVKLGLQGAVKAFAIQPNGTQTPLFTLNVDSDFSGKIWISDGRLKGSVKMDNVTLKLAASEVGTFSIDAMEKDVRLGVPVVVSLKVNKILDEGFVLPKIKQAQLVNSVLKVEEGFMAVFSDVELFLTDEGLN
    

Molecular Weight51942.02 Da

Isoelectric Point (pI)4.84

Net Charge (pH 7.0)-19.62

Net Charge (pH 7.4) -20.53

Charge Density (pH 7.0) -0.0411

GRAVY Index0.16

Hydrophobic Moment 0.72

Boman Index0.18

Instability Index32.89

Aliphatic Index 102.49

Aromaticity 0.0881

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147262 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabas testudineus (Climbing perch) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria