MYP_010735
Basic Information
Aurein 2.5
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Anti-biofilm Biofilm inhibition
Antimicrobial Antibiotic activity
Antimicrobial Antifungal
Immunology Innate immune defense Host defense peptide Defense peptide
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Toxicity / Safety Negative safety assay result Non-hemolytic
Venom / Toxin General toxin Cytotoxic
Standard
72 amino acids
C358H576N96O115S2
Standard
Sequence
MAFLKKSLFLVLFLGLVSLSICEKEKRQNEEDEDENEAANHEEGSEEKRGLFDIVKKVVGAFGSLGKRNDLE
Physicochemical Analysis
8129.11 Da
4.90
-5.39
-5.71
-0.0748
-0.47
0.79
-0.09
44.22
90.69
0.0694
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3465.36
-31.79
118.0
113.0
292.0
571.0
6.0
76.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025327 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
RECORD: Rec_0042896 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
RECORD: Rec_0186410 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
RECORD: Rec_0202487 VERIFIED: NO
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0425301 VERIFIED: YES
Provenance & Taxonomy
Ranoidea aurea [Animal]
Frog skin active peptide (FSAP); Aurein subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Defense peptide Antimicrobial Antibiotic Antifungal Antibiofilm Anti-Gram-negative Anti-Gram-positive Anticancer Non-hemolytic
Gram Negative Bacteria and Gram Positive Bacteria