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MYP_010716
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Basic Information
B1AW
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C123H205N31O27S2
Standard
Sequence
FLPLLAGLAANFLPQIICKIARKC
Physicochemical Analysis
2614.26 Da
9.50
2.74
2.50
0.1141
1.14
0.77
0.35
23.86
146.67
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
915.16
-3.35
32.0
32.0
84.0
183.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009290 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
H838
32.15 μM
IC50
PMID37228702 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37228702/
RECORD: Rec_0104931 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID37228702 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37228702/
RECORD: Rec_0156764 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Amolops wuyiensis [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
the peptide is toxic: hemolytic HC50 23.96 uM: highly hemolytic. Also HACaT cells
44.09 μM
IC50
PaperDiscovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue.
RECORD: Rec_0174357 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
33.46 μM
IC50
PMID37228702 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/37228702/
RECORD: Rec_0177256 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Amolops wuyiensis [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus ATCC 6538 or MRSA NCTC 12493
32 μM
MIC
PaperDiscovery and analysis of a novel antimicrobial peptide B1AW from the skin secretion of Amolops wuyiensis and improving the membrane-binding affinity through the construction of the lysine-introduced analogue.
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