Peptide Database

Peptide NameDefensin-5 (Defensin, alpha 5; primates, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC333H548N106O117S6

DescriptionStandard

        ESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRIGHCTILESLSGVCEISGRLYRLCCR
    

Molecular Weight8100.94 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0149

GRAVY Index-0.37

Hydrophobic Moment 0.69

Boman Index-0.11

Instability Index41.14

Aliphatic Index 75.60

Aromaticity 0.0400

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3665.73

LogP -50.78

H-bond Donors 137.0

H-bond Acceptors 123.0

Rotatable Bonds 277.0

Heavy Atoms 562.0

Ring Count 4.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0026869 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0048781 VERIFIED: NO