Peptide Database

Peptide NameEsculentin-1-OG4 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC406H683N107O118S4

DescriptionStandard

        MFTLKKSLLLIVLLGIISLSLCEQERAADEDEGSEIKRGLFSKFAGKGIKDLIFKGVKHIGKEVGTDVIRTGIDVAGCKIKGEC
    

Molecular Weight9079.67 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0187

GRAVY Index0.19

Hydrophobic Moment 0.73

Boman Index0.09

Instability Index13.45

Aliphatic Index 114.88

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3631.75

LogP -29.65

H-bond Donors 130.0

H-bond Acceptors 125.0

Rotatable Bonds 326.0

Heavy Atoms 635.0

Ring Count 5.0

Amide Bonds 84.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0264278 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

Tax ID167935

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal