MYP_010583
ANK6
—
Standard
12 amino acids
C69H136N28O14
Standard
RKRIRLVTKKKR
1582.00 Da
12.00
7.76
7.55
0.6463
-1.82
0.43
-1.05
56.42
89.17
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
755.33
-6.57
30.0
22.0
61.0
111.0
0.0
11.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0298468
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D-amino-acid peptide [D]
None
Amidation
C-terminal amidation; all-D residues
Bio-Activity Profile
Anti-amyloid
Amyloid-beta aggregation inhibitor
amyloid-β1-42
3.6 μM
IC50; Thioflavin T Aβ aggregation inhibition assay
RECORD: Rec_0431875
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
D-peptide Aβ-targeting inhibitor
Structure & Mods
linear peptide [Linear]
all-D-amino-acid peptide [D]
Amidation
C-terminal amidation; all-D residues
Bio-Activity Profile
Anti-amyloid
Cytoprotective
PC12 cells exposed to amyloid-β1-42
11 μM
IC50; Aβ1-42-induced cytotoxicity cell-viability assay
RECORD: Rec_0431876
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
D-peptide Aβ-targeting inhibitor
Structure & Mods
linear peptide [Linear]
all-D-amino-acid peptide [D]
Amidation
C-terminal amidation; all-D residues
Bio-Activity Profile
Anti-amyloid
Amyloid-beta oligomer elimination
amyloid-β1-42 oligomers
QIAD assay