Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC235H390N60O76

DescriptionStandard

        NEELGKKYEETKKKQEEFYKKIEEIEKKNEEVKKKLEELQKK
    

Molecular Weight5271.97 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0186

GRAVY Index-2.15

Hydrophobic Moment 0.65

Boman Index-0.59

Instability Index99.04

Aliphatic Index 53.33

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2338.65

LogP -17.36

H-bond Donors 77.0

H-bond Acceptors 77.0

Rotatable Bonds 206.0

Heavy Atoms 371.0

Ring Count 3.0

Amide Bonds 45.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0118566 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 78.6%, E 0.0%, T 7.1%, C 14.3% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0422658 VERIFIED: YES

Provenance & Taxonomy

OrganismFeline immunodeficiency virus [Virus]

FamilyVirus-derived peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetFeline immunodeficiency virus (Virus entry); HeLa

MethodSyncytia assay

PaperAntiviral activity of membrane fusion inhibitors that target gp40 of the feline immunodeficiency virus envelope protein. | Mizukoshi F, Baba K, Goto Y, Setoguchi A, Fujino Y, Ohno K, Oishi S, Kodera Y, Fujii N, Tsujimoto H. | Vet Microbiol. 2009 | PMID:19036536 PMID19036536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19036536/