‹ ›
MYP_010576
← PREVIOUS NEXT → BACK
Basic Information
RGD-Las
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C88H152N26O21
Standard
Sequence
RGDLLRHVVKILSKYL
Physicochemical Analysis
1910.31 Da
10.28
2.85
2.59
0.1778
0.13
0.79
-0.06
33.08
158.12
0.0625
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
782.10
-3.99
29.0
25.0
66.0
135.0
2.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0339275 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
A-549
50 μg/mL
Inhibition
PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0346725 VERIFIED: YES
Provenance & Taxonomy
Arg-Gly-Asp [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
rabbit erythrocytes and human erythrocytes at 250 μg/ml
PaperPubMed PMID: 22641352 PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0367124 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD-modified temporin analogs
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HL7702 (liver cancer)
50 μg/mL
MTT/MTS assay
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0394026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
RGD-modified temporin analogs
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
SW-1116 (colorectal cancer)
50 μg/mL
MTT/MTS assay
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0425913 VERIFIED: YES
Provenance & Taxonomy
Arg-Gly-Asp [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
(52.50 Inhibition ratio at 50 μg/ml)
PaperPubMed PMID: 22641352 PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
FIRST PREV 1 ... 4 5 6
Showing 5 records on this page · Page 6 of 6