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MYP_010538
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Basic Information
Ranatuerin-2SSa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C131H217N35O40S2
Standard
Sequence
GLISTIWNTASNVAGTLTDSVKCKFKKC
Physicochemical Analysis
2986.46 Da
9.31
2.74
2.50
0.0978
0.12
0.51
0.09
8.47
83.57
0.0714
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1233.98
-14.65
46.0
45.0
100.0
208.0
3.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0355268 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
mammalian cells (32 ug/ml, survival rates of COS7, HepG2
PaperAntimicrobial Property and Mode of Action of the Skin Peptides of the Sado Wrinkled Frog, Glandirana susurra, against Animal and Plant Pathogens.
RECORD: Rec_0375287 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 32751229 PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0390149 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human hepatocellular carcinoma HepG2
80-90 % Killing
Killing
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0412468 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Xanthomonas oryzae pv. oryzae MAFF 311018
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0418029 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 32751229 PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
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