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MYP_010538
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Basic Information
Ranatuerin-2SSa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C131H217N35O40S2
Standard
Sequence
GLISTIWNTASNVAGTLTDSVKCKFKKC
Physicochemical Analysis
2986.46 Da
9.31
2.74
2.50
0.0978
0.12
0.51
0.09
8.47
83.57
0.0714
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1233.98
-14.65
46.0
45.0
100.0
208.0
3.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0238055 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Monkey COS-7 cells
61.7 % Killing
Killing
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0267727 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
80.3 %
Cytotoxicity
PaperPubMed PMID: 32751229 PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0285018 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans JCM 2085
70-80 % Inhibition
Inhibition
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0292926 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa JCM 6119
20-30 % Inhibition
Inhibition
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
RECORD: Rec_0326042 VERIFIED: YES
Provenance & Taxonomy
Glandirana susurra [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pyricularia oryzae MAFF 101511
10-20 % Inhibition
Inhibition
PMID32751229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32751229/
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