Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC172H276N54O52S2

DescriptionStandard

        KCNTATCATQRLTHFLVRSSHHLGAVLPPTNVGSNTY
    

Molecular Weight3996.49 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)3.00

Net Charge (pH 7.4) 2.61

Charge Density (pH 7.0) 0.0811

GRAVY Index-0.20

Hydrophobic Moment 0.60

Boman Index0.02

Instability Index19.14

Aliphatic Index 73.78

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1703.86

LogP -22.90

H-bond Donors 62.0

H-bond Acceptors 60.0

Rotatable Bonds 124.0

Heavy Atoms 280.0

Ring Count 7.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094646 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla lanigera [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)