Peptide Database

Peptide NameBrevinin-1Sc

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC123H201N29O29S2

DescriptionStandard

        FFPIVAGVAGQVLKKIYCTISKKC
    

Molecular Weight2614.22 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1556

GRAVY Index0.82

Hydrophobic Moment 0.63

Boman Index0.29

Instability Index17.44

Aliphatic Index 109.58

Aromaticity 0.1250

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 931.69

LogP -5.04

H-bond Donors 34.0

H-bond Acceptors 35.0

Rotatable Bonds 86.0

Heavy Atoms 183.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389907 VERIFIED: YES

Provenance & Taxonomy

OrganismRana sphenocephala [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide18-24

Bio-Activity Profile

Function

Antimicrobial Antifungal

Targetpathogenic chytrid fungus B. dendrobatidis

Activity20 μM

MethodMIC

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