Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC387H652N106O95S4

DescriptionStandard

        MPKSLINIVKRLLGTRLKKKASKIVNMVMTGSDVASAISIVLGAFSFGTVTAIAWAARMSLKWYIKRKGKKKAAVTW
    

Molecular Weight8438.23 Da

Isoelectric Point (pI)11.67

Net Charge (pH 7.0)14.49

Net Charge (pH 7.4) 14.25

Charge Density (pH 7.0) 0.1882

GRAVY Index0.30

Hydrophobic Moment 0.78

Boman Index0.10

Instability Index14.27

Aliphatic Index 105.19

Aromaticity 0.0779

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3259.81

LogP -25.41

H-bond Donors 120.0

H-bond Acceptors 114.0

Rotatable Bonds 291.0

Heavy Atoms 592.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370962 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus safensis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal